BCL6 monoclonal antibody, clone GI191E/A8
产品名称: BCL6 monoclonal antibody, clone GI191E/A8
英文名称: BCL6 monoclonal antibody, clone GI191E/A8
产品编号: MAB10735
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against BCL6.
- Immunogen:
- BCL6.
- Host:
- Mouse
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (protein base, sodium azide)
- Storage Instruction:
- Store at 4°C is stable for 3 years.
- Quality Control Testing:
- Positive control use as lymph node, tonsil.
Visualization at nuclear.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunohistochemistry
- Entrez GeneID:
- 604
- Gene Name:
- BCL6
- Gene Alias:
- BCL5,BCL6A,LAZ3,ZBTB27,ZNF51
- Gene Description:
- B-cell CLL/lymphoma 6
- Omim ID:
- 109565
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- B-cell lymphoma 6 protein,B-cell lymphoma 6 protein transcript,cys-his2 zinc finger transcription factor,lymphoma-associated zinc finger gene on chromosome 3,zinc finger protein 51,zinc finger transcription factor BCL6S
- Related Disease
- Adenocarcinoma
- Central Nervous System Neoplasms
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Hematologic Diseases
- HIV Infections
- Hodgkin Disease
- Kidney Failure, Chronic
- Leukemia, chronic myeloid
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Lung Neoplasms
- Lymphoma, AIDS-Related
- Lymphoma, B-Cell
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Large-Cell, Diffuse
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Neovascularization, Pathologic