FITC标记的FAM29蛋白抗体
产品名称： FITC标记的FAM29蛋白抗体
英文名称： Anti-FAM29A/FITC
产品编号： HZ-9723R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-FAM29A/FITC Conjugated antibody
FITC标记的FAM29蛋白抗体
| 产品编号 | bs-9723R-FITC |
| 英文名称 | Anti-FAM29A/FITC |
| 中文名称 | FITC标记的FAM29蛋白抗体 |
| 别 名 | Dgt6; Dim gamma tubulin homolog; Family with sequence similarity 29 member A; FLJ20060; HAUS augmin like complex subunit 6; HAUS6; KIAA15741; HAUS6_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 109kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM29A/HAUS6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The human augmin complex (HAUS) is an evolutionarily conserved 8-subunit protein complex that was initially discovered in Drosophila. The HAUS complex is essential for microtubule generation, centrosome integrity, mitotic spindle assembly and completion of cytokinesis. HAUS6 (HAUS augmin-like complex, subunit 6), also known as FAM29A or Dgt6, is a 955 amino acid component of the augmin complex. Required for mitotic progression, HAUS6 localizes to cytoplasm, cytoskeleton, mitotic spindle microtubules and interphase centrosomes, and undergoes post-translational phosphorylation following mitosis on multiple serine and threonine residues. HAUS6 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 9. Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Promotes the nucleation of microtubules from the spindle through recruitment of NEDD1 and gamma-tubulin. Subunit: Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Interacts with PLK1 and NEDD1. Subcellular Location: Cytoplasm, Cytoskeleton, Microtubule Post-translational modifications: Phosphorylated during mitosis. Similarity: Belongs to the HAUS6 family. Database links: Entrez Gene: 54801 Human Omim: 613433 Human SwissProt: Q7Z4H7 Human Unigene: 533468 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
人类Aumin复合物（HAUs）是一种进化保守的8亚基蛋白复合物，最初在Drosophila发现。HAUS复合物对于微管的生成、中心体完整性、有丝分裂纺锤体的组装和胞质分裂的完成是必不可少的。HAUS6（HAU-Auxmin样复合物，亚基6），也称为FAM29 A或DGT6，是Aumin复合物的955个氨基酸组分。有丝分裂进程的需要，HAUS6定位到细胞质，细胞骨架，有丝分裂纺锤体微管和相间中心体，并经历翻译后磷酸化后多丝氨酸和苏氨酸残基的有丝分裂。HAUS6存在两个交替剪接的亚型，其由位于9号染色体上的基因编码。