PTPN9 (C-term) Peptide
产品名称： PTPN9 (C-term) Peptide
英文名称： PTPN9 (C-term) Peptide
产品编号： P3241
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTPN9.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PTPN9.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Purification and characterization of protein tyrosine phosphatase PTP-MEG2.
Qi Y, Zhao R, Cao H, Sui X, Krantz SB, Zhao ZJ.J Cell Biochem. 2002;86(1):79-89.
- 2.
- Protein-tyrosine phosphatase MEG2 is expressed by human neutrophils. Localization to the phagosome and activation by polyphosphoinositides.
Kruger JM, Fukushima T, Cherepanov V, Borregaard N, Loeve C, Shek C, Sharma K, Tanswell AK, Chow CW, Downey GP.J Biol Chem. 2002 Jan 25;277(4):2620-8. Epub 2001 Nov 15.
- 3.
- Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p.
Gu M, Warshawsky I, Majerus PW.Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2980-4.
- Applications
- Western Blot (Cell lysate)
- The PTPN9 polyclonal antibody (Cat # PAB4083) is used in Western blot to detect PTPN9 in A-549 cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with PTPN9 polyclonal antibody (Cat # PAB4083) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 5780
- Protein Accession#:
- P43378
- Gene Name:
- PTPN9
- Gene Alias:
- MEG2,PTPMEG2
- Gene Description:
- protein tyrosine phosphatase, non-receptor type 9
- Omim ID:
- 600768
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq
- Other Designations:
- PTPase-MEG2,protein-tyrosine phosphatase MEG2