FITC标记的葡萄糖6-磷酸脱氨酶2抗体
产品名称： FITC标记的葡萄糖6-磷酸脱氨酶2抗体
英文名称： Anti-GNPDA2/FITC
产品编号： HZ-13474R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GNPDA2/FITC Conjugated antibody
FITC标记的葡萄糖6-磷酸脱氨酶2抗体
| 英文名称 | Anti-GNPDA2/FITC |
| 中文名称 | FITC标记的葡萄糖6-磷酸脱氨酶2抗体 |
| 别 名 | GlcN6P deaminase 2; Glucosamine 6 phosphate deaminase 2; Glucosamine 6 phosphate isomerase 2; Glucosamine 6 phosphate isomerase SB52; Glucosamine-6-phosphate deaminase 2; Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate isomerase SB52; GNP2; GNPDA 2; Gnpda2; GNPI2_HUMAN; SB52. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GNPDA2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: During fertilization in mammals, the sperm activates the egg by causing an increase in the level of free cytoplasmic calcium concentration. This increased calcium concentration induces a characteristic series of oscillations that trigger egg activation and early embryo development. A hamster protein named oscillin is thought to be involved in this pathway. The enzyme glucosamine-6-phosphate isomerase (GNPI) or deaminase (GNPDA1) and the related protein GNPDA2 are the human homologs of hamster oscillin. GNPDA1 and GNPDA2 catalyze the conversion of GNP to fructose-6-phosphate and ammonia. Both proteins exist as homohexamers and are ubiquitously expressed with highest expression in testis, ovary and heart. Three isoforms of GNPDA2 are expressed due to alternative splicing events. Subunit: Homohexamer (By similarity). Subcellular Location: Cytoplasm. Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. Database links: UniProtKB/Swiss-Prot: Q8TDQ7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在哺乳动物的受精过程中，精子通过引起游离细胞质钙浓度的增加来激活卵子。这种增加的钙浓度引起一系列特征性的振荡，触发卵子激活和早期胚胎发育。一种名叫oscillin的仓鼠蛋白被认为参与了这一途径。葡萄糖胺-6-磷酸异构酶(GNPI)或脱氨酶(GNPDA1)及其相关蛋白GNPDA2是仓鼠奥西林的人类同源物。GnPDA1和GnPdA2催化GNP转化为果糖-6-磷酸和氨。两种蛋白均存在同源表达，在睾丸、卵巢和心脏中普遍表达。GnPdA2的三种异构体由于选择性剪接事件而表达。