LLGL1/LLGL2 (phospho S650/654) Peptide
产品名称： LLGL1/LLGL2 (phospho S650/654) Peptide
英文名称： LLGL1/LLGL2 (phospho S650/654) Peptide
产品编号： P1024
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of LLGL1/2.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S650/S654 of human LLGL1/2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer.
Schimanski CC, Schmitz G, Kashyap A, Bosserhoff AK, Bataille F, Schafer SC, Lehr HA, Berger MR, Galle PR, Strand S, Strand D.Oncogene. 2005 Apr 28;24(19):3100-9.
- 2.
- The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo.
Grifoni D, Garoia F, Schimanski CC, Schmitz G, Laurenti E, Galle PR, Pession A, Cavicchi S, Strand D.Oncogene. 2004 Nov 11;23(53):8688-94.
- 3.
- Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico.
Katoh M, Katoh M.Int J Oncol. 2004 Mar;24(3):737-42.
- Entrez GeneID:
- 3996
- Protein Accession#:
- NP_004131 (Gene ID : 3996);Q15334 (Gene ID : 3996);NP_004515 (Gene ID : 3993);Q6P1M3 (Gene ID : 3993)
- Gene Name:
- LLGL1
- Gene Alias:
- DLG4,HUGL,HUGL-1,HUGL1,LLGL
- Gene Description:
- lethal giant larvae homolog 1 (Drosophila)
- Omim ID:
- 600966
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
- Other Designations:
- lethal giant larvae homolog 1
- Entrez GeneID:
- 3993
- Protein Accession#:
- NP_004131 (Gene ID : 3996);Q15334 (Gene ID : 3996);NP_004515 (Gene ID : 3993);Q6P1M3 (Gene ID : 3993)
- Gene Name:
- LLGL2
- Gene Alias:
- HGL,LGL2
- Gene Description:
- lethal giant larvae homolog 2 (Drosophila)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- human giant larvae homolog,lethal giant larvae homolog 2