FITC标记的心磷脂酰基转移酶1抗体
产品名称： FITC标记的心磷脂酰基转移酶1抗体
英文名称： Anti-LCLAT1/FITC
产品编号： HZ-18190R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-LCLAT1/FITC Conjugated antibody
FITC标记的心磷脂酰基转移酶1抗体
| 英文名称 | Anti-LCLAT1/FITC |
| 中文名称 | FITC标记的心磷脂酰基转移酶1抗体 |
| 别 名 | 1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8; ALCAT1; HSRG1849; lclat1; LCLT1_HUMAN; LYCAT; Lysocardiolipin acyltransferase 1; UNQ1849; UNQ1849/PRO3579. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 49kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LCLAT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Expressed at higher level in heart, kidney and pancreas than in brain, spleen, liver, lung, small intestine and placenta. Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. Database links: Entrez Gene: 253558 Human Entrez Gene: 225010 Mouse Entrez Gene: 100217396 Pig Omim: 614241 Human SwissProt: Q6UWP7 Human SwissProt: Q3UN02 Mouse Unigene: 468048 Human Unigene: 662770 Human Unigene: 329194 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Acyl CoA：溶酶体心脂酰基转移酶。同时具有溶血磷脂酰肌醇酰基转移酶（LPIAT）和lysophosphatidylglycerol acyltransferase（LPGAT）活性。确认单溶性心磷脂和二酰基心磷脂作为底物，优先选择亚油酰基辅酶A和油酰基辅酶A作为酰基供体。作为心肌磷脂的重塑酶，是一种主要的膜聚甘油磷脂。将溶血磷脂酸（LPA）转化为具有相对低活性的磷脂酸（PA）。建立造血和内皮谱系所必需的。