CDH1 (Human) ELISA Kit
产品名称： CDH1 (Human) ELISA Kit
英文名称： CDH1 (Human) ELISA Kit
产品编号： KA0433
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- CDH1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CDH1.
- Calibration Range:
- 156 to 10000 pg/mL
- Limit of Detection:
- 15 pg/mL
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C for 4 months. For long term storage, please store at -20°C for 8 months.
- Quality Control Testing:
- Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
- Protocol:
Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Body Fluid, Cell Culture Supernatant, Plasma, Serum, Tissue Lysate
- Sample Volume:
- 100 uL
- Label:
- Biotin-conjugate
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.
Batlle E, Sancho E, Franci C, Dominguez D, Monfar M, Baulida J, Garcia De Herreros A.Nat Cell Biol. 2000 Feb;2(2):84-9.
- 2.
- Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).
Berx G, Staes K, van Hengel J, Molemans F, Bussemakers MJ, van Bokhoven A, van Roy F.Genomics. 1995 Mar 20;26(2):281-9.
- 3.
- E-cadherin gene mutations provide clues to diffuse type gastric carcinomas.
Becker KF, Atkinson MJ, Reich U, Becker I, Nekarda H, Siewert JR, Hofler H.Cancer Res. 1994 Jul 15;54(14):3845-52.
- Application Image
- Quantification
- Entrez GeneID:
- 999
- Gene Name:
- CDH1
- Gene Alias:
- Arc-1,CD324,CDHE,ECAD,LCAM,UVO
- Gene Description:
- cadherin 1, type 1, E-cadherin (epithelial)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq
- Other Designations:
- cadherin 1, E-cadherin (epithelial),cadherin 1, type 1,calcium-dependent adhesion protein, epithelial,cell-CAM 120/80,uvomorulin
- Related Disease
- Adenocarcinoma
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- Breast Neoplasms
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- Carcinoma, Large Cell
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