GAD1 (Human) Recombinant Protein (P01)
产品名称： GAD1 (Human) Recombinant Protein (P01)
英文名称： GAD1 (Human) Recombinant Protein (P01)
产品编号： H00002571-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GAD1 full-length ORF ( AAH26349, 1 a.a. - 594 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
- Theoretical MW (kDa):
- 91.08
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2571
- GeneBank Accession#:
- BC026349
- Protein Accession#:
- AAH26349
- Gene Name:
- GAD1
- Gene Alias:
- FLJ45882,GAD,SCP
- Gene Description:
- glutamate decarboxylase 1 (brain, 67kDa)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq
- Other Designations:
- OTTHUMP00000041055,glutamate decarboxylase 1,glutamate decarboxylase 1 (brain, 67kD)
- Related Disease
- Alcoholism
- Anxiety Disorders
- Autistic Disorder
- Bipolar Disorder
- Cleft Lip
- Cleft Palate
- Cognition
- Depressive Disorder
- Depressive Disorder, Major
- Disease Models, Animal
- Genetic Predisposition to Disease
- Hypercholesterolemia
- Kidney Failure, Chronic
- Mental Disorders
- Neuropsychological Tests
- Neurotic Disorders
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenia