PCCA抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PCCA抗体

PCCA抗体

商家询价

产品名称： PCCA抗体

英文名称： PCCAAntibody

产品编号： XY 21988-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802 点击查看
  • 传真 : 点击查看
  • 邮箱 : shxysw02@163.com
  • 二维码 : 点击查看
进入展台

 PCCA抗体Applications

In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 2 citations –view here
Species specificity Human, Mouse; other species not tested.
Published Species Mouse
Images
Prev12NextView more validation data
  • 21988-1-AP;L02 cellsL02 cells were subjected to SDS PAGE followed by western blot with 21988-1-AP(PCCA antibody) at dilution of 1:1000
  • 21988-1-AP;human liverImmunohistochemistry of paraffin-embedded human liver slide using 21988-1-AP( PCCA Antibody) at dilution of 1:50
  • 21988-1-AP;human liverImmunohistochemistry of paraffin-embedded human liver slide using 21988-1-AP( PCCA Antibody) at dilution of 1:50
  • 21988-1-AP;L02 cellsIP Result of anti-PCCA (IP:21988-1-AP, 4ug; Detection:21988-1-AP 1:1000) with L02 cells lysate 1800ug.
Positive WB detected in L02 cells, mouse liver tissue, NIH/3T3 cells
Positive IP detected in L02 cells
Positive IHC detected in Human liver tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
 PCCA抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen PCCA fusion protein ag17271 Full name Propionyl Coenzyme A carboxylase, alpha polypeptide
Calculated molecular
weight		 80 kDa Observed molecular 
weight		 70 kDa
GenBank accession 
number		 BC000140 Gene ID (NCBI) 5095
Gene symbol PCCA Synonyms PCCA, PCCase subunit alpha
Background PCCA抗体

Propionyl-CoA carboxylase (PCC) catalyzes the biotin-dependent carboxylation of propionyl-CoA to D-methyl-malonyl CoA, a reaction that occurs in the mitochondrial matrix. PCC is involved in the catabolism of several essential amino acids (methionine, isoleucine, threonine and valine), as well as odd chain fatty acids and cholesterol. Deficiency of PCC results in propionic acidemia, a metabolic disorder characterized by severe metabolic ketoacidosis, vomiting, lethargy and hypotonia. PCC consists of nonidentical subunits (α and β) encoded by different genes (PCCA and PCCB, respectively). The αPCC cDNA contains an open reading frame of 2106 nucleotide bases and codes for a 702 amino acid polypeptide. The mature length subunit is 70 kDa and contains the biotin binding site.(PMID:8852656). This protein has 3 isoforms produced by alternative splicing with the molecular weight of 80 kDa, 77 kDa and 75 kDa. The full length protein has a transit peptide with 52 amino acids. This antibody is specific to PCCA. PCCA抗体

XY615Hu22 Bcl2相关髓细胞白血病序列1(MCL1)单克隆抗体 Monoclonal Antibody to Myeloid Cell Leukemia Sequence 1, Bcl2 Related (MCL1) Homo sapiens (Hukl)

XY622Hu22 多聚蛋白1(MMRN1)单克隆抗体 Monoclonal Antibody to Multimerin 1 (MMRN1) Homo sapiens (Hukl)

XY625Hu22 巯基丙酮酸硫转移酶(MPST)单克隆抗体 Monoclonal Antibody to Mercaptopyruvate Sulfurtransferase (MPST) Homo sapiens (Hukl)

XY628Hu22 微精蛋白β(MSMβ)单克隆抗体 Monoclonal Antibody to Microseminoprotein Beta (MSMb) Homo sapiens (Hukl)

XY631Hu22 异粘蛋白(MTDH)单克隆抗体 Monoclonal Antibody to Metadherin (MTDH) Homo sapiens (Hukl)

XY642Hu22 膜突蛋白(MSN)单克隆抗体 Monoclonal Antibody to Moesin (MSN) Homo sapiens (Hukl)

XY646Hu22 肌微管素1(MTM1)单克隆抗体 Monoclonal Antibody to Myotubularin 1 (MTM1) Homo sapiens (Hukl)

XY659Hu22 胰岛素样生长因子结合蛋白5(IGFBP5)单克隆抗体 Monoclonal Antibody to Insulin Like Growth Factor Binding Protein 5 (IGFBP5) Homo sapiens (Hukl)

XY664Hu22 核仁磷酸蛋白(NPM)单克隆抗体 Monoclonal Antibody to Nucleophosmin (NPM) Homo sapiens (Hukl)

XY665Hu22 利钠肽受体1(NPR1)单克隆抗体 Monoclonal Antibody to Natriuretic Peptide Receptor 1 (NPR1) Homo sapiens (Hukl)

XY672Hu22 神经外营养蛋白1(NXPH1)单克隆抗体 Monoclonal Antibody to Neurexophilin 1 (NXPH1) Homo sapiens (Hukl)

XY684Hu22 2',5'-寡腺苷酸合成酶1(OAS1)单克隆抗体 Monoclonal Antibody to 2',5'-Oligoadenylate Synthetase 1 (OAS1) Homo sapiens (Hukl)

XY685Hu22 鸟氨酸脱羧酶抗酶1(OAZ1)单克隆抗体 Monoclonal Antibody to Ornithine Decarboxylase Antizyme 1 (OAZ1) Homo sapiens (Hukl)

XY688Hu22 骨诱导因子(OGN)单克隆抗体 Monoclonal Antibody to Osteoglycin (OGN) Homo sapiens (Hukl)

XY692Hu22 旋光蛋白(OPTC)单克隆抗体 Monoclonal Antibody to Opticin (OPTC) Homo sapiens (Hukl)

XY695Hu22 破骨细胞关联受体(OSCAR)单克隆抗体 Monoclonal Antibody to Osteoclast Associated Receptor (OSCAR) Homo sapiens (Hukl)

XY704Hu22 8-羟基鸟嘌呤糖苷酶1(OGG1)单克隆抗体 Monoclonal Antibody to Oxoguanine Glycosylase 1 (OGG1) Homo sapiens (Hukl)