CD7 monoclonal antibody, clone MEM-186 (FITC)
产品名称： CD7 monoclonal antibody, clone MEM-186 (FITC)
英文名称： CD7 monoclonal antibody, clone MEM-186 (FITC)
产品编号： MAB4540
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD7.
- Immunogen:
- Native purified CD7 from human acute myelogenous leukaemia cell line KG-1.
- Host:
- Mouse
- Theoretical MW (kDa):
- 40
- Reactivity:
- Human
- Specificity:
- The antibody reacts with CD7, a 40 KDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
- Form:
- Liquid
- Conjugation:
- FITC
- Isotype:
- IgG
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- CD7 expression predicts poor disease free survival and post-remission survival in patients with acute myeloid leukemia and normal karyotype.
Chang H, Yeung J, Brandwein J, Yi QL.Leuk Res. 2007 Feb;31(2):157-62. Epub 2006 Jul 11.
- 2.
- Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M.
Nishimura M, Takanashi M, Okazaki H, Satake M, Nakajima K.Endothelium. 2006 Jul-Aug;13(4):287-92.
- 3.
- Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma.
Lam GK, Liao HX, Xue Y, Alam SM, Scearce RM, Kaufman RE, Sempowski GD, Haynes BF.J Clin Immunol. 2005 Jan;25(1):41-9.
- Entrez GeneID:
- 924
- Gene Name:
- CD7
- Gene Alias:
- GP40,LEU-9,TP41,Tp40
- Gene Description:
- CD7 molecule
- Omim ID:
- 186820
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq
- Other Designations:
- CD7 antigen,CD7 antigen (p41),T-cell antigen CD7,T-cell leukemia antigen,p41 protein
- Gene Pathway