KLK6 (Human) Recombinant Protein (Q01)
产品名称： KLK6 (Human) Recombinant Protein (Q01)
英文名称： KLK6 (Human) Recombinant Protein (Q01)
产品编号： H00005653-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human KLK6 partial ORF ( AAH15525, 91 a.a. - 190 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- RAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGK
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia.
Ashby EL, Kehoe PG, Love S.Brain Res. 2010 Sep 13. [Epub ahead of print]
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5653
- GeneBank Accession#:
- BC015525
- Protein Accession#:
- AAH15525
- Gene Name:
- KLK6
- Gene Alias:
- Bssp,Klk7,MGC9355,NEUROSIN,PRSS18,PRSS9,SP59,ZYME,hK6
- Gene Description:
- kallikrein-related peptidase 6
- Omim ID:
- 602652
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq
- Other Designations:
- kallikrein 6 (neurosin, zyme),protease M,protease, serine, 18,protease, serine, 9