CDKN1C polyclonal antibody
产品名称: CDKN1C polyclonal antibody
英文名称: CDKN1C polyclonal antibody
产品编号: PAB25634
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CDKN1C.
- Immunogen:
- A synthetic peptide corresponding to 17 amino acids at N-terminus of human CDKN1C.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 35
- Reactivity:
- Human
- Specificity:
- At least three isoforms of CDKN1C are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, CDKN1C often migrates at 57kDa in SDS-PAGE. CDKN1C antibody is predicted to not cross react with other CIP/KIP proteins.
- Form:
- Liquid
- Purification:
- Peptide affinity purification
- Concentration:
- 1 mg/mL
- Isotype:
- IgG
- Storage Buffer:
- In PBS (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 1028
- Protein Accession#:
- NP_000067
- Gene Name:
- CDKN1C
- Gene Alias:
- BWCR,BWS,KIP2,WBS,p57
- Gene Description:
- cyclin-dependent kinase inhibitor 1C (p57, Kip2)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000011736,cyclin-dependent kinase inhibitor 1C
- Gene Pathway
- Related Disease
- Atherosclerosis
- Atherosclerosis
- Birth Weight
- Cleft Lip
- Cleft Palate
- Diabetes Mellitus, Type 2
- Genetic Predisposition to Disease
- Lung Neoplasms
- Multiple endocrine neoplasia
- Multiple Endocrine Neoplasia Type 1
- Myocardial Infarction
- Neoplasms, Glandular and Epithelial
- Ovarian cancer
- Ovarian Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Werner syndrome