BAG3 抗体
Applications
| In-house applications |
ELISA, WB, IF, IP, IHC Application not tested? Please see our Guarantee. |
| Published applications |
IF, IHC, IP, WB |
Publications |
16 citations –view here |
| Species specificity |
Human,Mouse,Rat; other species not tested. |
| Published Species |
Human, monkey, mouse |
|
Images
Prev12Next
 HeLa cells were subjected to SDS PAGE followed by western blot with 10599-1-AP(BAG3 antibody) at dilution of 1:1000 IP Result of anti-BAG3 (IP:10599-1-AP, 4ug; Detection:10599-1-AP 1:1000) with K-562 cells lysate 11000ug. Immunofluorescent analysis of Hela cells, using BAG3 antibody 10599-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 10599-1-AP( BAG3 Antibody) at dilution of 1:50 (under 10x lens) Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 10599-1-AP( BAG3 Antibody) at dilution of 1:50 (under 40x lens)
|
| Positive WB detected in |
HeLa cells, DU 145 cells, HEK-293 cells, K-562 cells, mouse brain tissue, mouse placenta tissue, mouse uterus tissue, rat brain tissue |
| Positive IP detected in |
K-562 cells |
| Positive IHC detected in |
Human gliomas tissue |
| Positive IF detected in |
Hela cells |
| Recommended dilution |
WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100 |
BAG3 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
| Source |
Rabbit |
Purification method |
Antigen affinity purification |
| Isotype |
IgG |
Storage |
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen |
BAG3 fusion protein ag0956 |
Full name |
BCL2-associated athanogene 3 |
Calculated molecular
weight |
61 kDa |
Observed molecular
weight |
74-80 kDa |
GenBank accession
number |
BC006418 |
Gene ID (NCBI) |
9531 |
| Gene symbol |
BAG3 |
Synonyms |
BAG 3, BAG3, BIS, CAIR 1, Docking protein CAIR 1 |
Background BAG3 抗体
|
BAG3 (Bcl2-associated athanogene 3) belongs to the BAG protein family, the co-chaperone that binds to Hsc70/Hsp70 through the BAG domain and modulates their activity in polypeptide folding. BAG3 contains also a WW domain and a proline-rich (PXXP) repeat, that mediate binding to partners different from Hsp70. Through interacting with different molecular partner, BAG3 influences several cell processes, such as apoptosis, autophagy and cell motility. BAG3 protein has been reported to sustain cell survival, resistance to therapy, and/or motility and metastatization in several tumor types, thus being identified as a potential target for anticancer therapies. In addition, defects in BAG3 are the cause of some myopathy. BAG3 normally migrates around 74-80 kD; a slightly different molecular weight or a doublet form can be observed in some cell types and/or following cell exposure to stressors. A synaptosome associated form of 40 kD has recently been described. BAG3 抗体
|
XY033Ga21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Chicken (Gallus)
XY033Gu21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Cavia (Guinea pig )
XY033Ov21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Ovis aries; Ovine (Sheep)
XY033Po21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Sus scrofa; Porcine (Pig)
XY033Ra21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Rattus norvegicus (Rat)
XY033Rb21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Oryctolagus cuniculus (Rabbit)
XY033Si21 干扰素α(IFNα)单克隆抗体 Monoclonal Antibody to Interferon Alpha (IFNa) Rhesus monkey (Simian)
XY034Bo21 成纤维细胞生长因子4(FGF4)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) Bos taurus; Bovine (Cattle)
XY034Ga21 成纤维细胞生长因子4(FGF4)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) Chicken (Gallus)
XY034Ra21 成纤维细胞生长因子4(FGF4)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 4 (FGF4) Rattus norvegicus (Rat)
XY035Fi21 成纤维细胞生长因子6(FGF6)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 6 (FGF6) Danio rerio (Zebrafish)
XY035Ra21 成纤维细胞生长因子6(FGF6)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 6 (FGF6) Rattus norvegicus (Rat)
XY036Bo21 成纤维细胞生长因子9(FGF9)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) Bos taurus; Bovine (Cattle)
XY036Ga21 成纤维细胞生长因子9(FGF9)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) Chicken (Gallus)
XY036Ra21 成纤维细胞生长因子9(FGF9)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 9 (FGF9) Rattus norvegicus (Rat)
