GAC-specific抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
GAC-specific抗体

GAC-specific抗体

商家询价

产品名称: GAC-specific抗体

英文名称: GAC-specificAntibody

产品编号: XY19958-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 GAC-SPECIFIC抗体

Applications
In-house applications ELISA, IHC, WB, IP     Application not tested? Please see our Guarantee.
Published applications WB Publications 4 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human
Images
Prev12NextView more validation data
  • 19958-1-AP;human heartImmunohistochemical of paraffin-embedded human heart using 19958-1-AP(GAC-specific antibody) at dilution of 1:50 (under 10x lens)
  • 19958-1-AP;human heartImmunohistochemical of paraffin-embedded human heart using 19958-1-AP(GAC-specific antibody) at dilution of 1:50 (under 40x lens)
  • 19958-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 19958-1-AP( GAC-specific Antibody) at dilution of 1:600
  • 19958-1-AP;mouse kidney tissueIP Result of anti-GAC-specific (IP:19958-1-AP, 3ug; Detection:19958-1-AP 1:500) with mouse kidney tissue lysate 4000ug.
Positive WB detected in HEK-293 cells, mouse kidney tissue
Positive IP detected in Mouse kidney tissue
Positive IHC detected in Human heart tissue, human kidney tissue, human pancreas cancer tissue
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200
 GAC-SPECIFIC抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information GAC-SPECIFIC抗体
Immunogen Peptide Full name Glutaminase
Calculated molecular
weight
65 kDa Observed molecular 
weight
60-65 kDa
GenBank accession 
number
AF158555 Gene ID (NCBI) 2744
Gene symbol GLS Synonyms AAD20, DKFZp686O15119, FLJ10358, GAC, GAC-specific, GLS, GLS1, glutaminase C, K glutaminase, KIAA0838, L glutamine amidohydrolase
Background

Glutaminase C (GAC), a splicing variant of the kidney-type glutaminase (KGA) gene, is a vital mitochondrial enzyme protein that catalyzes glutamine to glutamate. GAC is the only isoform present in the mitochondria (PMID:22228304). In a normal state, immunodecorationwith antibodies directed against GAC identified an abundant complex of 232 kDa as a tetrameric form of GAC, the DPAA can directly destructed the native tetrameric GAC complex to accumulate the unassembled one (50-90 kDa). (PMID:22493432). This antibody is specific to GAC isoform. It has no cross reaction to KGA. GAC-SPECIFIC抗体

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