FITC标记的多肽N-乙酰氨基半乳糖转移酶1抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的多肽N-乙酰氨基半乳糖转移酶1抗体

FITC标记的多肽N-乙酰氨基半乳糖转移酶1抗体

商家询价

产品名称: FITC标记的多肽N-乙酰氨基半乳糖转移酶1抗体

英文名称: Anti-GALNT1/FITC

产品编号: HZ-13273R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-GALNT1/FITC Conjugated antibody

FITC标记的多肽N-乙酰氨基半乳糖转移酶1抗体

 

英文名称 Anti-GALNT1/FITC
中文名称 FITC标记的多肽N-乙酰氨基半乳糖转移酶1抗体
别    名 GALNAC T1; GalNAc transferase 1; GalNAc-T1; GALNT 1; GALNT1; GALT1_HUMAN; Polypeptide GalNAc transferase 1; Polypeptide N acetylgalactosaminyltransferase 1; Polypeptide N-acetylgalactosaminyltransferase 1 soluble form; pp GaNTase 1; pp-GaNTase 1; Protein UDP acetylgalactosaminyltransferase 1; Protein-UDP acetylgalactosaminyltransferase 1; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 1; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1 (GalNAc T1); UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GALNT1/GalNAc-T1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T1, also known as GALNT1 (Polypeptide N-acetylgalactosaminyltransferase 1), is a ubiquitously expressed 559 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and, like other GalNAc-Ts, contains a stem region and a C-terminal ricin/lectin-like domain. GalNAc-T1 catalyzes the first reaction in O-linked oligosaccharide biosynthesis, namely the transfer of an N-acetyl-D-galactosamine residue to a protein acceptor. GalNAc-T1 uses calcium and manganese as cofactors. Due to alternative splicing events, two GalNAc-T1 isoforms are expressed.

Function:
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7.

Subcellular Location:
Secreted and Golgi apparatus > Golgi stack membrane.

Tissue Specificity:
Widely expressed. Expressed in all tissues tested.

Similarity:
Belongs to the glycosyltransferase 2 family.
GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain.

Database links:

Entrez Gene: 2589 Human

Entrez Gene: 14423 Mouse

Entrez Gene: 79214 Rat

Omim: 602273 Human

SwissProt: Q10472 Human

SwissProt: O08912 Mouse

SwissProt: Q10473 Rat

Unigene: 514806 Human

Unigene: 30249 Mouse

Unigene: 10266 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

UDP-N-乙酰-α-D-半乳糖胺:多肽N-乙酰半乳糖胺基转移酶(GalNAc-T)家族是底物特异性蛋白,催化GalNAc(N-乙酰半乳糖胺)向丝氨酸和苏氨酸残基转移至各种蛋白质上,从而引发粘蛋白型O链。高尔基体中的ED糖基化。GalNAc-T1,也称为GALNT1(多肽N-乙酰半乳糖胺基转移酶1),是一种广泛表达的559个氨基酸单程II型膜蛋白,定位于高尔基体,与其他GalNAc-Ts一样,含有茎区和C端蓖麻毒素/凝集素样结构域。GalNAc-T1催化O连接寡糖生物合成中的第一反应,即N-乙酰-D-半乳糖胺残基向蛋白质受体的转移。GalNC-T1使用钙和锰作为辅因子。由于选择性剪接事件,表达了两个GalNC-T1亚型。