FITC标记的臂板蛋白3F抗体
产品名称： FITC标记的臂板蛋白3F抗体
英文名称： Anti-Semaphorin 3F/FITC
产品编号： HZ-1122R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Semaphorin 3F/FITC Conjugated antibody
FITC标记的臂板蛋白3F抗体
| 英文名称 | Anti-Semaphorin 3F/FITC |
| 中文名称 | FITC标记的臂板蛋白3F抗体 |
| 别 名 | Semaphorin-3F; Semaphorin3F; Sema III/F; Sema IV; sema3F; SemaIII/F; SemaIV; Semaphorin IV; SemaphorinIV; SEM3F_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 发育生物学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 88kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Sema3F |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family. Function: May play a role in cell motility and cell adhesion. Subunit: Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Sema domain. Subcellular Location: Secreted. Tissue Specificity: Expressed abundantly but differentially in a variety of neural and nonneural tissues. There is high expression in mammary gland, kidney, fetal brain, and lung and lower expression in heart and liver. Database links: Entrez Gene: 6405 Human Entrez Gene: 20350 Mouse Entrez Gene: 315996 Rat Omim: 601124 Human SwissProt: Q13275 Human SwissProt: O88632 Mouse Unigene: 32981 Human Unigene: 12903 Mouse Unigene: 205616 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SimaPrrin是一类参与信号传递的蛋白质家族。所有家族成员都具有分泌信号、500个氨基酸的sema结构域和16个保守的半胱氨酸残基(Kolodkin等人，1993[PubMed 8269517])。序列比较将分泌的信号素分成3类，它们都具有免疫球蛋白结构域。信号素III家族由人信号素III（SEMA3A；MIM 603961）、鸡胶原蛋白和小鼠信号素A、D和E组成，在C端都有基本结构域。鸡胶原蛋白通过与相对分子质量62K(CRMP62)的胶原蛋白反应介质蛋白相互作用，抑制生长锥的延伸，从而有助于轴突在发育过程中的路径发现(Ro等人，1993[PubMed 8402908])(Goshima等人，1995[PubMed7637782])，p与轴突导向相关的UN33基因产物（MIM 601168）的同源性。SEMA3F是SimaPrIGIN家族的一个分泌成员。