PI4KA polyclonal antibody
产品名称： PI4KA polyclonal antibody
英文名称： PI4KA polyclonal antibody
产品编号： PAB3227
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PI4KA.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PI4KA.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Association of T cell antigen CD7 with type II phosphatidylinositol-4 kinase, a key component in pathways of inositol phosphate turnover.
Subrahmanyam G, Rudd CE, Schneider H.Eur J Immunol. 2003 Jan;33(1):46-52.
- 2.
- Parallel activation of phosphatidylinositol 4-kinase and phospholipase C by the extracellular calcium-sensing receptor.
Huang C, Handlogten ME, Miller RT.J Biol Chem. 2002 Jun 7;277(23):20293-300. Epub 2002 Mar 20.
- 3.
- Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230.
Gehrmann T, Gulkan H, Suer S, Herberg FW, Balla A, Vereb G, Mayr GW, Heilmeyer LM Jr.Biochim Biophys Acta. 1999 Mar 25;1437(3):341-56.
- Applications
- Western Blot (Tissue lysate)
- The PI4KA polyclonal antibody (Cat # PAB3227) is used in Western blot to detect PI4KA in human placenta tissue lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PI4KA polyclonal antibody (Cat # PAB3227) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 5297
- Protein Accession#:
- P42356
- Gene Name:
- PI4KA
- Gene Alias:
- FLJ16556,PI4K-ALPHA,PIK4CA,pi4K230
- Gene Description:
- phosphatidylinositol 4-kinase, catalytic, alpha
- Omim ID:
- 600286
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- phosphatidylinositol 4-kinase 230,phosphatidylinositol 4-kinase type 3 alpha,phosphatidylinositol 4-kinase, type III, alpha