EIF5,真核翻译起始因子5抗体

产品编号HZ-2913R
英文名称EIF5
中文名称真核翻译起始因子5抗体
别 名EIF 5; EIF 5A; Eukaryotic initiation factor 5; Eukaryotic translation initiation factor 5; IF5_HUMAN.
说 明 书0.1ml 0.2ml
研究领域免疫学 染色质和核信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit,
EIF5,真核翻译起始因子5抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EIF5
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EIF5,真核翻译起始因子5抗体PubMedPubMed
产品介绍background:
EIF5, Eukaryotic initiation factor 5, catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex.

Function:
Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

Similarity:
Belongs to the eIF-2-beta/eIF-5 family.
Contains 1 W2 domain.

Database links:
UniProtKB/Swiss-Prot: P55010.2

EIF5,真核翻译起始因子5抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.