FITC标记的HRAS样抑制因子3抗体
产品名称： FITC标记的HRAS样抑制因子3抗体
英文名称： Anti-Hrasls3/FITC
产品编号： HZ-2145R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Hrasls3/FITC Conjugated antibody
FITC标记的HRAS样抑制因子3抗体
| 英文名称 | Anti-Hrasls3/FITC |
| 中文名称 | FITC标记的HRAS样抑制因子3抗体 |
| 别 名 | H rev 107 protein homolog; HRAS like suppressor 3; HREV107 3; HREV107; Renal carcinoma antigen NY REN 65; Adipose specific phospholipase A2; Group XVI phospholipase A2; HREV107; HRSL3_MOUSE; AdPLA; HRSL3; HRASLS3; HREV107-1; HREV107-3; H-REV107-1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from the middle of mouse Hrasls3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: HRASLS3 specifically catalyzes the release of fatty acids from phospholipids in adipose tissue and also has a weak lysophospholipase activity. It is a tumor suppressor that may be involved in interferon-dependent cell death. Function: Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue. N-and O-acylation activity is hardly detectable. Also has weak lysophospholipase activity. Subunit: Interacts with PPP2R1A; this interaction might decrease PP2A activity. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm, perinuclear region. Tissue Specificity: Ubiquitously expressed in normal tissues but down-regulated in primary carcinomas or in many cell lines derived from tumors. Highly expressed in white adipose tissue and in adipocytes. Expressed at lower levels in brown adipose tissue. Similarity: Belongs to the H-rev107 family. Database links: Entrez Gene: 11145 Human Entrez Gene: 225845 Mouse Omim: 613867 Human SwissProt: P53816 Human SwissProt: Q8R3U1 Mouse Unigene: 502775 Human Unigene: 274810 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
HRASLS3特异性催化脂肪组织中磷脂的脂肪酸释放，并且具有弱的溶血磷脂酶活性。它是一种可能参与干扰素依赖性细胞死亡的肿瘤抑制因子。