FITC标记的细胞色素c氧化酶亚型2抗体
产品名称: FITC标记的细胞色素c氧化酶亚型2抗体
英文名称: Anti-MTCO2/Cytochrome c oxidase subunit 2/FITC
产品编号: HZ-2376R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-MTCO2/Cytochrome c oxidase subunit 2/FITC Conjugated antibody
FITC标记的细胞色素c氧化酶亚型2抗体
英文名称 | Anti-MTCO2/Cytochrome c oxidase subunit 2/FITC |
中文名称 | FITC标记的细胞色素c氧化酶亚型2抗体 |
别 名 | Cytochrome c oxidase polypeptide II; MT-CO2; COII; COXII; MTCO2; COX2; Cytochrome c oxidase II; Cytochrome c oxidase subunit 2; COX2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 转录调节因子 线粒体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Cytochrome c oxidase subunit 2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. DISEASE: Defects in MT-CO2 are a cause of mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]; also known as cytochrome c oxidase deficiency. A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, excercise intolerance, developmental delay, delayed motor development and mental retardation. A subset of patients manifest Leigh syndrome. Similarity: Belongs to the cytochrome c oxidase subunit 2 family. Database links: Entrez Gene: 4513 Human Omim: 516040 Human SwissProt: P00403 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
细胞色素C氧化酶是催化氧还原为水的呼吸链的一个组成部分。亚基1-3形成酶复合物的功能核心。亚基2通过细胞色素C通过双核铜中心转移到催化亚基1的双金属中心。